Leptin hormone function


   

Leptin hormone function


Leptin hormone function


      More or less, everything that happens in the human body can be explained by the action of one or another hormone. Figuratively speaking, hormones are the messengers that give orders to cells what to do. 


      You cannot exercise control over the levels of individual hormones. You can't say to yourself, "Hmm ... let me secrete some testosterone." But you can influence hormonal balance through the choices you make every day: what food you eat, how you deal with stress, how and how much you exercise, and how much sleep you get.

One essential hormone that you should learn more about is leptin.


What is leptin?


Leptin hormone function


     Leptin is a hormone that regulates energy intake and energy expenditure in the body. Leptin is a protein secreted by fat cells transported through the blood to the receptors of the hypothalamus (a gland located in the brain). When leptin levels are low, hunger is uncontrollable. When the receptors in the hypothalamus have not lost their sensitivity and leptin is present, appetite is suppressed.

Through the secretion of leptin, the cells tell the brain that there is enough stored fat, and everything is fine. In other words, when leptin levels are above a certain threshold (probably for each person this threshold is genetically determined), the brain receives a signal that the body has enough fat reserves and no need to store extra. That is, the energy received through food is not stored in fat depots, but is fully used for other functions.



       When you follow an extremely low-calorie diet (so to speak, the famous fruit diets), the body starves, and leptin levels fall below the threshold. When this happens, the brain creates a feeling of hunger, telling you, "Hey, I'm not getting as much energy as before. I need more food." As a result, several processes begin through which the body tries to revive leptin levels. The vagus, which makes the connection between the brain and also the system, plays a vital role here. 

  


             Once activated, the nervus vagus sends signals that stimulate hunger. The body tries to force you to urge more energy to store as fat and restore leptin levels. How does leptin affect body weight? The question is: If the body regulates hunger and appetite, why can we still gain weight? The problem is that overweight people don't stop eating, and also, the brain doesn't receive a symptom to prevent loading fat stores. But why doesn't it get that signal? Because of a condition called leptin resistance . Leptin levels may still rise as people even gain weight.



Lepin hormone function


     Leptin resistance, leptin levels are high, which means that you are overweight, but your brain does not "see" it. In other words, your mind is starving while your body is obese. We can say that obesity is brain starvation


      When leptin levels are low, it isn't easy to get enough from food. When leptin levels are high, you don't have to eat that much, and the food doesn't look so appealing. But in people with leptin resistance, the sensitivity of the receptors is reduced, and the brain does not receive a sign that the energy intake is high. So the hunger does not pass, and you will continue to eat until you enter a vicious cycle.


 Is there a solution?


     There is, of course, but it is not simple. You must first limit or best stop refined carbohydrates, fructose, and transfat. It would help if you strived to minimize saturated fats and include low glycemic index carbohydrates . Eat more foods rich in healthy fats such as fish, raw nuts, avocados, olive oil, hemp milk, and others.

Another important thing is not to overeat but to eat less and more often to increase leptin sensitivity. Limit your calorie intake by up to 15-20% of your calorie balance.


Symptoms of leptin resistance


The most common symptoms are:

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  • A feeling of hunger that does not go away (mostly craving for sweet and sugars).
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  • Increased appetite late in the day, but mainly before bedtime.
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  • Weight gain at the expense of adipose tissue.
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  • It is difficult and even impossible to get rid of excess fat.
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  • Disturbed sleep and fatigue during the day

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